Visit the iconic Duomo di Milano or see some of Leonardo da Vinci’s most famous artworks this year — round-trip flights to Milan from multiple U.S. cities are as low as $445. An array of carriers are offering discounted flights to Milan from many major U.S. cities such as New York, Chicago and San Francisco. The travel dates for these deals to Milan are from February through March and from October through December. Certain routes are also available during Thanksgiving, but Christmas is completely excluded from these deals. Flights to Milan are typically expensive, and these cheap fares are expected to only last a couple of days. Plan your trip…